Saskatoon Police Service says on Wednesday the Guns and Gangs Unit was staked-out at an address in the 300 block of Avenue G South after receiving information someone may be in possession of firearms.
Police saw four people exit the building and all were arrested without incident.
Officers conducted a search of their persons and say two 17-year-old males were in possession of loaded guns. A third 17-year-old male was arrested on unrelated warrants and a 21-year-old woman was released without charges.
A .22 calibre sawed off rifle and a .22 calibre handgun were seized by police. Two individuals are facing several charges relating to prohibited and restricted weapons.